{"id":19568,"date":"2020-02-10T15:50:17","date_gmt":"2020-02-10T14:50:17","guid":{"rendered":"https:\/\/www.generationsanstabac.org\/actualites\/larret-du-tabac-permet-la-multiplication-de-cellules-bronchiques-saines\/"},"modified":"2020-02-10T15:50:17","modified_gmt":"2020-02-10T14:50:17","slug":"larret-du-tabac-permet-la-multiplication-de-cellules-bronchiques-saines","status":"publish","type":"actualites","link":"https:\/\/www.generationsanstabac.org\/en\/actualites\/larret-du-tabac-permet-la-multiplication-de-cellules-bronchiques-saines\/","title":{"rendered":"Quitting smoking allows healthy bronchial cells to multiply"},"content":{"rendered":"<p><strong> <\/strong>Researchers from the Wellcome Trust Sanger Institute and University College London, UK, report in an article published on January 29, 2020 in the journal Nature that inhaling tobacco smoke contributes to adding 1,000 to 10,000 new mutations (more than a quarter of which are potentially carcinogenic) per bronchial cell to spontaneous mutations. These mutations, which can be of different natures, are directly responsible for the occurrence of bronchial\/lung cancers, which are the leading cause of cancer death due to tobacco.<\/p>\n<p>The good news concerns smokers who have quit, because the number of mutations observed in their bronchial cells gradually returns to the same level as that observed in the bronchial cells of never-smokers, which ultimately results in a reduced risk of developing cancer. Thus, the epithelial lining of the bronchi gradually becomes &quot;healthy&quot; again. This repopulation is likely carried out from cells that have escaped the genetic damage linked to tobacco smoke observed in their neighbors, these &quot;healthy&quot; cells being four times more frequent in ex-smokers than in smokers.<\/p>\n<p>These results explain, at least in part, why quitting smoking is effective at any age in preventing the development of lung cancer. However, they do not predict the development of other tobacco-related respiratory diseases, such as chronic obstructive pulmonary disease (COPD), namely emphysema and chronic bronchitis.<\/p>\n<p><span style=\"color: #666699;\"><a style=\"color: #666699;\" href=\"https:\/\/www.generationsanstabac.org\/en\/\">\u00a9Generation Without Tobacco<\/a><\/span><\/p>\n<hr \/>\n<div class=\"entry-content\">\n<p><span style=\"color: #e8e8e8;\"><a style=\"color: #e8e8e8;\" href=\"http:\/\/www.cnct.fr\/\" target=\"_blank\" rel=\"noopener noreferrer\">| \u00a9National Committee Against Smoking |<\/a><\/span><\/p>\n<\/div>\n<div class=\"date-wrapper\">\n<div class=\"grid-container\"><\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>the number of mutations observed in their bronchial cells gradually returns to that observed in never-smokers<\/p>","protected":false},"featured_media":19480,"template":"","tags":[],"thematique":[474],"class_list":["post-19568","actualites","type-actualites","status-publish","has-post-thumbnail","hentry","thematique-sante"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.generationsanstabac.org\/en\/wp-json\/wp\/v2\/actualites\/19568","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.generationsanstabac.org\/en\/wp-json\/wp\/v2\/actualites"}],"about":[{"href":"https:\/\/www.generationsanstabac.org\/en\/wp-json\/wp\/v2\/types\/actualites"}],"version-history":[{"count":0,"href":"https:\/\/www.generationsanstabac.org\/en\/wp-json\/wp\/v2\/actualites\/19568\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.generationsanstabac.org\/en\/wp-json\/wp\/v2\/media\/19480"}],"wp:attachment":[{"href":"https:\/\/www.generationsanstabac.org\/en\/wp-json\/wp\/v2\/media?parent=19568"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.generationsanstabac.org\/en\/wp-json\/wp\/v2\/tags?post=19568"},{"taxonomy":"thematique","embeddable":true,"href":"https:\/\/www.generationsanstabac.org\/en\/wp-json\/wp\/v2\/thematique?post=19568"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}